Description

2-(Chloromethyl)-5-Methoxypyrazine is a versatile pyrazine derivative, a key heterocyclic building block prized for its reactive chloromethyl group and methoxy substituent. This compound is essential for introducing the 5-methoxypyrazine moiety into more complex molecular architectures, enabling the synthesis of advanced intermediates. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing potential drug candidates, particularly in medicinal chemistry research targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the pyrazine core contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Flavor and Fragrance Chemistry: Acts as an intermediate for synthesizing complex aroma compounds, as methoxypyrazines are known for their distinctive green, earthy notes.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as novel semiconductors or light-emitting compounds.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	2-(Chloromethyl)-5-Methoxypyrazine
CAS No.	1196156-90-7
Molecular Formula	C6H7ClN2O
Molecular Weight	158.59 g/mol
Synonyms	5-Methoxy-2-(chloromethyl)pyrazine; 2-Chloromethyl-5-methoxypyrazine; 5-Methoxy-2-pyrazinemethanol, chloride; (5-Methoxypyrazin-2-yl)methyl chloride; 2-Pyrazinemethanol, 5-methoxy-, chloride
EINECS	Contact for details

Quality Control

Our 2-(Chloromethyl)-5-Methoxypyrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.