Description

2-Amino-5-Fluoronicotinic Acid is a high-purity fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique chemical structure, which enables the introduction of both amino and carboxylic acid functionalities into complex molecular frameworks. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized to create fluorescent tags or molecular probes for biochemical and diagnostic research.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis projects requiring precise fluorination and functionalization.

Basic Information

Product Name	2-Amino-5-Fluoronicotinic Acid
CAS No.	1196154-03-6
Molecular Formula	C6H5FN2O2
Molecular Weight	156.11 g/mol
Synonyms	5-Fluoro-2-aminonicotinic Acid; 2-Amino-5-fluoropyridine-3-carboxylic Acid; 3-Carboxy-5-fluoro-2-aminopyridine; 5-Fluoro-2-aminopyridine-3-carboxylic Acid; 1196154-03-6; 2-Amino-5-fluoro-3-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-5-Fluoronicotinic Acid is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, NMR, and mass spectrometry, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and away from direct light and moisture to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.