Description

2-Chloro-5-Ethynylpyrazine is a high-value pyrazine derivative featuring both a chloro and an ethynyl functional group, making it a versatile and reactive building block for advanced chemical synthesis. This compound is critical for researchers and manufacturers requiring precise molecular architecture in complex organic frameworks. It is primarily utilized in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive pyrazine core.
• Material Science: Acts as a monomer or cross-linking agent in the creation of specialty polymers and advanced organic electronic materials.
• Chemical Research: Employed in academic and industrial R&D for exploring novel heterocyclic chemistry and click chemistry reactions via its alkyne group.
• Ligand Synthesis: Useful for constructing complex ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Chloro-5-Ethynylpyrazine
CAS No.	1196153-73-7
Molecular Formula	C6H3ClN2
Molecular Weight	138.56 g/mol
Synonyms	5-Ethynyl-2-chloropyrazine; 2-Chloro-5-ethynylpyrazine; 2-Chloro-5-ethynyl-1,4-diazine; 5-Ethynyl-2-chloro-1,4-diazine; 2-Chloropyrazine-5-ethyne; 2-Chloro-5-(ethynyl)pyrazine
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Ethynylpyrazine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.