Description

2-Ethynyl-6-Methoxy-Pyrazine is a specialized heterocyclic building block featuring both an ethynyl and a methoxy substituent on a pyrazine core. This compound is valued for its unique reactivity profile, making it a crucial intermediate in advanced organic synthesis and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that require specific heterocyclic scaffolds.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of conductive polymers and advanced organic electronic materials.
• Ligand Synthesis: Utilized in organometallic chemistry for creating novel ligands used in catalysis and coordination chemistry.
• Chemical Biology Probes: Acts as a core structure for developing molecular probes and tags due to its alkyne functionality for click chemistry applications.
• Flavor & Fragrance Chemistry: Investigated as a potential precursor for high-value aroma chemicals, given the pyrazine family's significance in flavor profiles.

Basic Information

Product Name	2-Ethynyl-6-Methoxy-Pyrazine
CAS No.	1196153-43-1
Molecular Formula	C7H6N2O
Molecular Weight	134.14 g/mol
Synonyms	6-Methoxy-2-ethynylpyrazine; 2-Ethynyl-6-methoxypyrazine; 2-Methoxy-6-ethynylpyrazine; Pyrazine, 2-ethynyl-6-methoxy-; (6-Methoxypyrazin-2-yl)acetylene
EINECS	Contact for details

Quality Control

Our 2-Ethynyl-6-Methoxy-Pyrazine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.