Description

5-Bromo-1H-Pyrazolo[3,4-B]Pyrazine is a high-purity, advanced pharmaceutical intermediate and heterocyclic building block, essential for modern drug discovery and development. Its core value lies in its unique fused pyrazolo-pyrazine structure, which serves as a critical scaffold for synthesizing novel bioactive compounds targeting various therapeutic areas. This compound is primarily needed by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in developing kinase inhibitors, oncology treatments, and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in oncology and kinase inhibitor research.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Serves as a precursor for developing molecular probes to study biological pathways and enzyme functions.
• Agrochemical Development: Potential application as an intermediate in the synthesis of new crop protection agents and pesticides.
• Material Science Research: Investigated as a precursor for organic electronic materials due to its electron-deficient heterocyclic core.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	5-Bromo-1H-Pyrazolo[3,4-B]Pyrazine
CAS No.	1196152-90-5
Molecular Formula	C5H3BrN4
Molecular Weight	198.99 g/mol
Synonyms	5-Bromo-1H-pyrazolo[3,4-b]pyrazine; 5-Bromo-1H-pyrazolo[3,4-b]pyrazine; 1H-Pyrazolo[3,4-b]pyrazine, 5-bromo-; 5-Bromo-1H-pyrazolo[3,4-b]pyrazine; 5-Bromopyrazolo[3,4-b]pyrazine; 5-Bromo-1H-pyrazolo[3,4-b]pyrazine; 5-Bromo-1H-pyrazolo[3,4-b]pyrazine (CAS 1196152-90-5)
EINECS	Contact for details

Quality Control

Our 5-Bromo-1H-Pyrazolo[3,4-B]Pyrazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specifications and test results. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.