Description

1-(2-Bromo-5-Hydroxypyridin-4-Yl)Ethanone is a high-purity brominated pyridinone derivative, serving as a critical building block in advanced organic synthesis. Its unique halogenated structure makes it an indispensable intermediate for constructing complex molecules with tailored biological and chemical properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core for bioactivity.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and liquid crystal materials.
• Chemical Synthesis: Acts as a versatile electrophile in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing complex heterocyclic systems.
• Academic & Contract Research: Employed in medicinal chemistry programs and process development for scale-up optimization.

Basic Information

Product Name	1-(2-Bromo-5-Hydroxypyridin-4-Yl)Ethanone
CAS No.	1196152-59-6
Molecular Formula	C7H6BrNO2
Molecular Weight	216.03 g/mol
Synonyms	4-Acetyl-2-bromo-5-hydroxypyridine; 2-Bromo-5-hydroxy-4-acetylpyridine; 1-(2-Bromo-5-hydroxypyridin-4-yl)ethan-1-one; 4-Acetyl-5-hydroxy-2-bromopyridine; Ethanone, 1-(2-bromo-5-hydroxy-4-pyridinyl)-; 2-Bromo-4-acetyl-5-hydroxypyridine; 1-(2-Bromo-5-hydroxypyridin-4-yl)ethanone
EINECS	Contact for details

Quality Control

Our 1-(2-Bromo-5-Hydroxypyridin-4-Yl)Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.