Description

5-(Trifluoromethyl)Pyrazine-2-Carbaldehyde is a high-value fluorinated pyrazine building block, essential for introducing the trifluoromethyl group and aldehyde functionality into complex molecular architectures. Its unique structure makes it a critical intermediate for synthesizing advanced materials and bioactive compounds where electronic properties and metabolic stability are paramount. This compound is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and transition metal catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-withdrawing properties.
• Fluorinated Compound Library: A valuable building block for constructing diverse fluorinated compound libraries for high-throughput screening in drug and agrochemical discovery.

Basic Information

Product Name	5-(Trifluoromethyl)Pyrazine-2-Carbaldehyde
CAS No.	1196151-36-6
Molecular Formula	C6H3F3N2O
Molecular Weight	176.10 g/mol
Synonyms	5-(Trifluoromethyl)-2-pyrazinecarboxaldehyde; 2-Pyrazinecarboxaldehyde, 5-(trifluoromethyl)-; 5-Trifluoromethylpyrazine-2-carboxaldehyde; 5-(Trifluoromethyl)pyrazinecarbaldehyde; 5-Trifluoromethyl-2-pyrazinecarbaldehyde; 5-(Trifluoromethyl)-2-formylpyrazine; 2-Formyl-5-(trifluoromethyl)pyrazine
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethyl)Pyrazine-2-Carbaldehyde is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support our clients' regulatory needs and ensure our products meet the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.