Description

4-[[3-[(5-Ethynyl-2-Pyridinyl)Oxy]Phenyl]Methyl]-n-3-Pyridinyl-1-Piperidinecarboxamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of targeted therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing novel drug candidates, especially in oncology and neurological disease research.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel small-molecule drug candidates targeting specific biological pathways.
• Kinase Inhibitor Research: Used in the development and optimization of potent and selective kinase inhibitors for oncology applications.
• Medicinal Chemistry R&D: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Probe Synthesis: Employed to create tool compounds for investigating protein function and signaling mechanisms in cellular assays.
• Preclinical Development: Supplied for the production of batches required for pharmacological and toxicological studies.
• Contract Manufacturing: Sourced by CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	4-[[3-[(5-Ethynyl-2-Pyridinyl)Oxy]Phenyl]Methyl]-n-3-Pyridinyl-1-Piperidinecarboxamide
CAS No.	1196109-53-1
Molecular Formula	C25H24N4O2
Molecular Weight	412.49 g/mol
Synonyms	4-({3-[(5-Ethynylpyridin-2-yl)oxy]phenyl}methyl)-N-(pyridin-3-yl)piperidine-1-carboxamide; 4-[[3-[(5-Ethynyl-2-pyridinyl)oxy]phenyl]methyl]-N-3-pyridinyl-1-piperidinecarboxamide; 1196109-53-1; UNII-1R6J7L0Z3F; 1R6J7L0Z3F; BDBM50380885; AKOS025147064; CHEMBL3185220
EINECS	Contact for details

Quality Control

Our production of 4-[[3-[(5-Ethynyl-2-Pyridinyl)Oxy]Phenyl]Methyl]-n-3-Pyridinyl-1-Piperidinecarboxamide adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with research-grade and cGMP standards for preclinical use. Our quality commitment supports reliable and reproducible results in critical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.