Description

4-Chloro-3-Fluoro-2-Methylpyridine is a high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which provides a versatile scaffold for constructing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated structure for enhanced bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to its electron-withdrawing characteristics.
• Custom Synthesis and Contract Manufacturing: A vital substrate for custom synthesis projects and scale-up processes in fine chemical production.
• Academic and R&D Laboratories: Used in methodological studies and exploratory chemistry to develop new synthetic routes and reactions.

Basic Information

Product Name	4-Chloro-3-Fluoro-2-Methylpyridine
CAS No.	1195251-01-4
Molecular Formula	C6H5ClFN
Molecular Weight	145.56 g/mol
Synonyms	2-Methyl-4-chloro-3-fluoropyridine; 3-Fluoro-4-chloro-2-methylpyridine; 4-Chloro-3-fluoro-2-picoline; 2-Picoline, 4-chloro-3-fluoro-; Pyridine, 4-chloro-3-fluoro-2-methyl-; FCMP (abbreviation); Halogenated 2-methylpyridine derivative
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-3-Fluoro-2-Methylpyridine is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider using an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.