Description

Indicine Hydrochloride is a hydrochloride salt derivative of the pyrrolizidine alkaloid indicine, a compound of significant interest in pharmaceutical research and development. Its primary value lies in its role as a key chemical reference standard and a crucial intermediate for synthesizing novel therapeutic agents. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors, particularly those focused on oncology and metabolic pathway studies. Indicine Hydrochloride CAS NO 1195140-94-3 is supplied under stringent quality control to ensure reliability for critical applications.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for quality control, method validation, and regulatory compliance in drug development and manufacturing.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a critical building block in the multi-step synthesis of potential drug candidates, especially in oncology research.
• Biochemical Research: Employed in in vitro and in vivo studies to investigate biological activity, metabolic pathways, and mechanism of action.
• Analytical Chemistry: Utilized for developing and calibrating analytical methods such as HPLC, LC-MS, and NMR for alkaloid detection and quantification.
• Academic & Contract Research: A vital reagent for universities and CROs (Contract Research Organizations) conducting fundamental research on natural products and their derivatives.

Basic Information

Product Name	Indicine Hydrochloride
CAS No.	1195140-94-3
Molecular Formula	C15H25NO5 • HCl
Molecular Weight	335.83 g/mol (free base: 299.36 g/mol)
Synonyms	Indicine HCl; (+)-Indicine Hydrochloride; Indicine Monohydrochloride; (7R,8R)-7-[(2R,3R,4S,5R,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-7,8,9,10-tetrahydro-5H-pyrrolizine-1,8-dicarbaldehyde Hydrochloride; NSC-132319 Hydrochloride; Pyrrolizidine Alkaloid Hydrochloride
EINECS	Contact for details

Quality Control

Every batch of Indicine Hydrochloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity requirements for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as identity, purity (by HPLC), and impurity profile. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Any individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.