Description

Ethyl 3-Hydroxy-2-oxopyrazine-1(2H)-carboxylate is a high-purity pyrazine derivative serving as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex heterocyclic scaffolds, enabling the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and scale-up synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the pyrazine core for bioactivity.
• Chemical Synthesis: Serves as a versatile precursor for the preparation of more complex heterocyclic compounds and functionalized pyrazines.
• Material Science: Potential monomer or additive in the research of specialty polymers and organic electronic materials.
• Academic & Contract Research: Essential reagent for methodological studies and custom synthesis projects in university and CRO laboratories.

Basic Information

Product Name	Ethyl 3-Hydroxy-2-oxopyrazine-1(2H)-carboxylate
CAS No.	1194374-12-3
Molecular Formula	C7H8N2O4
Molecular Weight	184.15 g/mol
Synonyms	Ethyl 3-hydroxypyrazine-2-carboxylate 1-oxide; 1-Carbethoxy-3-hydroxypyrazin-2-one 1-oxide; 3-Hydroxy-1,2-dihydropyrazine-2-one 1-carboxylic acid ethyl ester; Ethyl 3-hydroxy-2-oxo-1,2-dihydropyrazine-1-carboxylate; 1-Ethoxycarbonyl-3-hydroxypyrazin-2(1H)-one 1-oxide; Pyrazine derivative CAS 1194374-12-3
EINECS	Contact for details

Quality Control

Our Ethyl 3-Hydroxy-2-oxopyrazine-1(2H)-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.