Description

Cyclopropyl(2,3-Dihydro-1,4-Benzodioxin-6-Yl)Methanamine Hydrochloride is a high-purity organic compound primarily utilized as a key intermediate in advanced pharmaceutical research and development. Its unique molecular architecture, featuring a cyclopropyl and benzodioxin moiety, makes it a valuable building block for synthesizing novel active pharmaceutical ingredients (APIs) targeting central nervous system and cardiovascular disorders. This product is essential for medicinal chemists and process development scientists in pharmaceutical, biotechnology, and fine chemical industries seeking reliable, high-quality intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and cardiovascular research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new therapeutic agents.
• Process Chemistry Development: Serves as a key starting material (KSM) or advanced intermediate in scaling up API synthesis under Good Manufacturing Practice (GMP) conditions.
• Biochemical Research: Employed as a reference standard or a ligand precursor in biochemical assays and receptor binding studies.
• Fine Chemical Synthesis: Utilized in the preparation of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	Cyclopropyl(2,3-Dihydro-1,4-Benzodioxin-6-Yl)Methanamine Hydrochloride
CAS No.	1193388-06-5
Molecular Formula	C₁₄H₁₈ClNO₂
Molecular Weight	267.75 g/mol
Synonyms	6-[(Cyclopropylamino)methyl]-2,3-dihydro-1,4-benzodioxine hydrochloride; 1,4-Benzodioxin-6-methanamine, N-cyclopropyl-, hydrochloride; Cyclopropyl(1,4-benzodioxan-6-ylmethyl)amine hydrochloride; (6-((Cyclopropylamino)methyl)-2,3-dihydrobenzo[b][1,4]dioxine hydrochloride); CPBDM HCl; CAS 1193388-06-5
EINECS	Contact for details

Quality Control

Our Cyclopropyl(2,3-Dihydro-1,4-Benzodioxin-6-Yl)Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the stringent requirements for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.