Description

1-(2-Iodobenzoyl)Piperazine Hydrochloride is a high-purity, synthetically valuable chemical building block, primarily utilized in advanced pharmaceutical research and development. This compound is critical for medicinal chemists as it provides a versatile scaffold for creating novel drug candidates, particularly in the exploration of central nervous system (CNS) and receptor-targeted therapies. Its primary application is in the synthesis of active pharmaceutical ingredients (APIs) and complex organic molecules for preclinical studies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Chemical Synthesis: Serves as a versatile precursor for constructing complex piperazine-containing heterocycles and pharmacophores.
• Biochemical Research: Employed in the development of molecular probes and ligands for studying biological pathways and receptor interactions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the life sciences industry.

Basic Information

Product Name	1-(2-Iodobenzoyl)Piperazine Hydrochloride
CAS No.	1193387-17-5
Molecular Formula	C11H12IN2O·HCl
Molecular Weight	350.59 g/mol
Synonyms	1-(2-Iodobenzoyl)piperazine hydrochloride; 1-(2-Iodobenzoyl)piperazine HCl; 2-Iodo-N-(piperazin-1-yl)benzamide hydrochloride; Piperazine, 1-(2-iodobenzoyl)-, hydrochloride; 1193387-17-5; (2-Iodophenyl)(piperazin-1-yl)methanone hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(2-Iodobenzoyl)Piperazine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.