Description

1-[2-Oxo-2-(Piperazin-1-Yl)Ethyl]Pyrrolidine-2,5-Dione Hydrochloride is a high-purity, non-natural amino acid derivative and a key pharmaceutical intermediate. This compound is valued for its role as a sophisticated building block in the synthesis of complex active pharmaceutical ingredients (APIs) and novel chemical entities. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery, process development, and the production of targeted therapeutics.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of protease inhibitors, kinase inhibitors, and other small-molecule drug candidates.
• Peptidomimetic Research: Used in the design and development of peptide analogs and mimetics to enhance metabolic stability and bioavailability.
• Chemical Biology Probes: Serves as a precursor for creating labeled compounds or affinity probes to study enzyme function and biological pathways.
• Process Chemistry & Scale-up: Employed in route scouting and optimization for the efficient, large-scale manufacturing of target molecules.
• Academic & Institutional R&D: Utilized in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	1-[2-Oxo-2-(Piperazin-1-Yl)Ethyl]Pyrrolidine-2,5-Dione Hydrochloride
CAS No.	1193387-07-3
Molecular Formula	C10H16ClN3O3
Molecular Weight	261.71 g/mol
Synonyms	1-[2-Oxo-2-(1-Piperazinyl)ethyl]-2,5-pyrrolidinedione hydrochloride; 1-(2-Oxo-2-piperazin-1-ylethyl)pyrrolidine-2,5-dione hydrochloride; N-(2-Oxo-2-(piperazin-1-yl)ethyl)succinimide hydrochloride; Succinimide-piperazine amide hydrochloride; Piperazine-1-carboxylic acid (2,5-dioxopyrrolidin-1-yl)amide hydrochloride
EINECS	Contact for details

Quality Control

Our 1-[2-Oxo-2-(Piperazin-1-Yl)Ethyl]Pyrrolidine-2,5-Dione Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.