Description

2-Bromo-5-(Methylsulfinyl)Pyridine is a high-value, multi-functional heterocyclic building block characterized by its bromine and methylsulfinyl substituents. This compound is essential for facilitating advanced molecular construction in pharmaceutical and agrochemical research, enabling precise structural modifications and the introduction of key functional groups. It is primarily utilized by R&D chemists and process development scientists in the fine chemical and life science industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the pyridine core and sulfoxide moiety contribute to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for constructing specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials and liquid crystals.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules in proteomics and diagnostic assay development.

Basic Information

Product Name	2-Bromo-5-(Methylsulfinyl)Pyridine
CAS No.	1193244-96-0
Molecular Formula	C6H6BrNOS
Molecular Weight	220.09 g/mol
Synonyms	2-Bromo-5-(methylsulfinyl)pyridine; 5-Bromo-2-(methylsulfinyl)pyridine; Pyridine, 2-bromo-5-(methylsulfinyl)-; 2-Bromo-5-methylsulfinylpyridine; 2-Bromo-5-(methanesulfinyl)pyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-(Methylsulfinyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles against our stringent in-house specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.