Description

4-Iodo-2-(Methylsulfonyl)Pyridine is a high-value, multi-functional heterocyclic building block characterized by its reactive iodine and electron-withdrawing methylsulfonyl substituent. This compound is essential for facilitating advanced cross-coupling reactions and serving as a key precursor in the synthesis of complex molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in creating novel herbicides, fungicides, and insecticides by acting as a core scaffold for structure-activity relationship (SAR) studies.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The iodine moiety makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig couplings to introduce the pyridine core.
• Medicinal Chemistry & Drug Discovery: Employed in high-throughput screening and combinatorial chemistry to generate diverse compound libraries for biological testing.
• Chemical Biology Probes: Used to develop molecular probes and tags for studying biological processes and protein interactions.

Basic Information

Product Name	4-Iodo-2-(Methylsulfonyl)Pyridine
CAS No.	1193244-95-9
Molecular Formula	C7H6INO2S
Molecular Weight	295.10 g/mol
Synonyms	2-(Methylsulfonyl)-4-iodopyridine; 4-Iodo-2-methanesulfonylpyridine; Pyridine, 4-iodo-2-(methylsulfonyl)-; 4-Iodo-2-(methylsulfonyl)pyridine; 1193244-95-9
EINECS	Contact for details

Quality Control

Our 4-Iodo-2-(Methylsulfonyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.