Description

4-Chloro-2-(Difluoromethyl)Pyridine Hydrochloride is a high-purity, halogenated pyridine derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, leveraging the difluoromethyl and chloro substituents for enhanced bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis and materials science.
• Chemical Research: Employed in academic and industrial R&D for exploring new heterocyclic chemistry and fluorination methodologies.
• Material Science Precursor: Potential building block for the synthesis of functionalized polymers and advanced organic materials.

Basic Information

Product Name	4-Chloro-2-(Difluoromethyl)Pyridine Hydrochloride
CAS No.	1193104-11-8
Molecular Formula	C7H5Cl2F2N
Molecular Weight	220.03 g/mol
Synonyms	2-(Difluoromethyl)-4-chloropyridine hydrochloride; 4-Chloro-2-difluoromethylpyridine hydrochloride; 4-Chloro-2-(difluoromethyl)pyridinium chloride; Pyridine, 4-chloro-2-(difluoromethyl)-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-(Difluoromethyl)Pyridine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements of our global clientele. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.