Description

3-(Pyridin-4-Yl)-1-Trityl-1H-Indazol-5-Amine is a high-purity, advanced pharmaceutical intermediate featuring a unique indazole core functionalized with pyridine and trityl protecting groups. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of targeted kinase inhibitors and other bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors seeking to accelerate novel drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, especially kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Chemical Biology Probes: Serves as a core scaffold for developing molecular probes to study enzyme function and cellular pathways.
• Process Chemistry Development: Employed in route scouting and scale-up optimization for Active Pharmaceutical Ingredient (API) manufacturing.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.
• Academic Research: Used in university and institutional labs for fundamental research in heterocyclic and organic chemistry.

Basic Information

Item	Details
Product Name	3-(Pyridin-4-Yl)-1-Trityl-1H-Indazol-5-Amine
CAS No.	1192873-43-0
Molecular Formula	C31H24N4
Molecular Weight	452.55 g/mol
Synonyms	5-Amino-3-(4-pyridinyl)-1-trityl-1H-indazole; 1-Trityl-3-(4-pyridinyl)-1H-indazol-5-amine; 3-(4-Pyridyl)-1-trityl-1H-indazol-5-amine; 1H-Indazol-5-amine, 3-(4-pyridinyl)-1-(triphenylmethyl)-; 3-Pyridin-4-yl-1-trityl-1H-indazol-5-ylamine; 5-Amino-1-trityl-3-(4-pyridyl)indazole; CAS 1192873-43-0
EINECS	Contact for details

Quality Control

Every batch of 3-(Pyridin-4-Yl)-1-Trityl-1H-Indazol-5-Amine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.