Description

5H-Thiazolo[3,2-A]Pyrimidin-5-One, 7-[(1E)-2-[2-(Cyclopropylmethoxy)-3-Methoxyphenyl]Ethenyl]-6-[4-(Trifluoromethoxy)Phenyl]- is a high-value, complex heterocyclic compound that serves as a critical advanced intermediate in modern pharmaceutical research and development. This compound matters because its unique molecular architecture, featuring a thiazolopyrimidone core with specific aryl and ethenyl substituents, is designed to impart targeted biological activity. It is primarily needed by medicinal chemistry and process development teams within the pharmaceutical and biotechnology industries for the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new active pharmaceutical ingredients (APIs).
• Chemical Biology Probe: Acts as a tool compound for investigating specific biological targets and mechanisms of action in early-stage discovery.
• Process Chemistry Development: Employed in scaling up synthetic routes and optimizing manufacturing processes for novel therapeutics.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the life sciences sector.

Basic Information

Item	Details
Product Name	5H-Thiazolo[3,2-A]Pyrimidin-5-One, 7-[(1E)-2-[2-(Cyclopropylmethoxy)-3-Methoxyphenyl]Ethenyl]-6-[4-(Trifluoromethoxy)Phenyl]-
CAS No.	1192871-27-4
Molecular Formula	C26H21F3N2O4S
Molecular Weight	514.52 g/mol
Synonyms	7-[(1E)-2-[2-(Cyclopropylmethoxy)-3-methoxyphenyl]ethenyl]-6-[4-(trifluoromethoxy)phenyl]-5H-thiazolo[3,2-a]pyrimidin-5-one; 7-[(E)-2-[2-(Cyclopropylmethoxy)-3-methoxyphenyl]vinyl]-6-[4-(trifluoromethoxy)phenyl]thiazolo[3,2-a]pyrimidin-5-one; Thiazolo[3,2-a]pyrimidin-5-one derivative (CAS 1192871-27-4); Advanced Pharmaceutical Intermediate 1192871-27-4; TRPC6 inhibitor intermediate; Complex heterocyclic building block.
EINECS	Contact for details

Quality Control

Our 5H-Thiazolo[3,2-A]Pyrimidin-5-One derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.