Description

3-(Trifluoromethyl)Pyrazin-2(1H)-One is a high-value fluorinated pyrazinone derivative, a key heterocyclic building block prized for its unique physicochemical profile. Its core value lies in introducing the metabolically stable and lipophilic trifluoromethyl group into complex molecular architectures, significantly altering biological activity and material properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a critical intermediate in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial synthon for the research and synthesis of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Active Ingredient Development: Used in the design and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances efficacy and environmental stability.
• Material Science Research: Serves as a specialized monomer or precursor for developing novel fluorinated polymers and advanced organic electronic materials with tailored properties.
• Chemical Synthesis & Process Development: Employed as a versatile building block in organic synthesis for constructing complex heterocycles and in scaling up production processes for fine chemicals.
• Life Sciences & Biochemical Research: Utilized as a probe or labeled compound in biochemical assays and diagnostic research due to its distinct fluorine signature.

Basic Information

Product Name	3-(Trifluoromethyl)Pyrazin-2(1H)-One
CAS No.	1191035-90-1
Molecular Formula	C5H3F3N2O
Molecular Weight	164.09 g/mol
Synonyms	3-(Trifluoromethyl)-1H-pyrazin-2-one; 3-(Trifluoromethyl)-2(1H)-pyrazinone; 2-Hydroxy-3-(trifluoromethyl)pyrazine; 3-Trifluoromethyl-2-hydroxypyrazine; 3-Trifluoromethylpyrazin-2-ol; 1H-Pyrazin-2-one, 3-(trifluoromethyl)-; TFMPO
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)Pyrazin-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.