Description

3-Cyclopropylpyrazin-2-Amine is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrazine core substituted with a cyclopropyl group. This compound is of significant commercial interest for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Serves as a building block for developing new generation pesticides and herbicides with specific mode-of-action targets.
• Ligand Synthesis: Used in medicinal chemistry for creating complex ligands in catalyst systems and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors & fragrances.
• Academic & R&D: A valuable reagent for university laboratories and corporate R&D departments exploring new heterocyclic chemistry and structure-activity relationships (SAR).
• Bioconjugation Chemistry: Potential use in the development of antibody-drug conjugates (ADCs) and other biopharmaceutical linker systems.

Basic Information

Product Name	3-Cyclopropylpyrazin-2-Amine
CAS No.	1190969-76-6
Molecular Formula	C7H9N3
Molecular Weight	135.17 g/mol
Synonyms	2-Amino-3-cyclopropylpyrazine; 3-Cyclopropyl-2-pyrazinamine; 3-Cyclopropylpyrazin-2-ylamine; Cyclopropylpyrazinamine; 2-Pyrazinamine, 3-cyclopropyl-; (3-Cyclopropyl-pyrazin-2-yl)-amine
EINECS	Contact for details

Quality Control

Our 3-Cyclopropylpyrazin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.