Description

2H-Pyrrolo[2,3-B]Pyridin-2-One,1,3-Dihydro-4-Iodo- is a high-purity iodinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active compounds.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its versatile reactive sites.
• Agrochemical Development: Employed in the research and synthesis of new active ingredients for crop protection products.
• Material Science Precursor: Acts as a monomer or functional unit in the development of advanced organic electronic materials and polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2H-Pyrrolo[2,3-B]Pyridin-2-One,1,3-Dihydro-4-Iodo-
CAS No.	1190321-89-1
Molecular Formula	C7H5IN2O
Molecular Weight	260.03 g/mol
Synonyms	4-Iodo-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one; 4-Iodo-2H-pyrrolo[2,3-b]pyridin-2-one, 1,3-dihydro-; 1,3-Dihydro-4-iodo-2H-pyrrolo[2,3-b]pyridin-2-one; 4-Iodo-1H-pyrrolo[2,3-b]pyridin-2(3H)-one; 4-Iodopyrrolo[2,3-b]pyridin-2(1H)-one; 4-Iodo-7-azaindolin-2-one; Iodinated Pyrrolopyridinone Building Block
EINECS	Contact for details

Quality Control

Our 2H-Pyrrolo[2,3-B]Pyridin-2-One,1,3-Dihydro-4-Iodo- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques like HPLC, NMR, and mass spectrometry. Our quality system is designed to meet the stringent requirements of pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling should be performed under appropriate conditions to minimize degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.