Description

2-Oxo-2,3-Dihydro-1H-Pyrrolo[2,3-B]Pyridine-5-Carbonitrile is a high-value pharmaceutical intermediate and heterocyclic building block of significant interest in modern organic synthesis. Its core value lies in its fused pyrrolopyridine scaffold, which serves as a privileged structure for developing novel bioactive molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the discovery and development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially kinase inhibitors and other targeted therapies.
• Organic Synthesis Building Block: Used to construct fused heterocyclic systems for medicinal chemistry and material science applications.
• Research & Development (R&D): Essential for academic and industrial research exploring new chemical entities (NCEs) and structure-activity relationships (SAR).
• Agrochemical Research: Potential intermediate in the development of novel herbicides or pesticides with specific modes of action.
• Chemical Biology Probes: Utilized in the design of molecular probes to study biological pathways and protein functions.

Basic Information

Product Name	2-Oxo-2,3-Dihydro-1H-Pyrrolo[2,3-B]Pyridine-5-Carbonitrile
CAS No.	1190321-76-6
Molecular Formula	C8H5N3O
Molecular Weight	159.15 g/mol
Synonyms	1H-Pyrrolo[2,3-b]pyridine-5-carbonitrile, 2,3-dihydro-2-oxo-; 2-Oxo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine-5-carbonitrile; 5-Cyano-1H-pyrrolo[2,3-b]pyridin-2(3H)-one; 5-Cyano-2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-2-one; Pyrrolo[2,3-b]pyridine-5-carbonitrile, 2,3-dihydro-2-oxo-; 1190321-76-6
EINECS	Contact for details

Quality Control

Our 2-Oxo-2,3-Dihydro-1H-Pyrrolo[2,3-B]Pyridine-5-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.