Description

6-Fluoro-1H-Pyrrolo[3,2-B]Pyridine is a high-value fluorinated heterocyclic building block, specifically a substituted pyrrolopyridine derivative. This compound is of significant interest for its role as a key intermediate in modern pharmaceutical and agrochemical research, enabling the synthesis of novel active ingredients. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for constructing complex molecular architectures. The precise introduction of fluorine atoms into heterocyclic scaffolds is a critical strategy for modulating the biological activity, metabolic stability, and physicochemical properties of candidate molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential drug candidates, particularly in oncology, CNS disorders, and anti-infective research.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atom enhances bioactivity and environmental stability.
• Material Science Precursor: Serves as a starting material for creating advanced organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology Probe: Employed in the design of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and fine chemical companies for bespoke synthesis projects requiring specialized fluorinated heterocycles.

Basic Information

Product Name	6-Fluoro-1H-Pyrrolo[3,2-B]Pyridine
CAS No.	1190320-33-2
Molecular Formula	C7H5FN2
Molecular Weight	136.13 g/mol
Synonyms	6-Fluoro-1H-pyrrolo[3,2-b]pyridine; 6-Fluoro-1H-pyrrolo[3,2-b]pyridine; 1H-Pyrrolo[3,2-b]pyridine, 6-fluoro-; 6-Fluoropyrrolo[3,2-b]pyridine; 6-Fluoro-7-azaindole; 6-Fluoro-1H-7-azaindole; 6-F-AZA
EINECS	Contact for details

Quality Control

We supply 6-Fluoro-1H-Pyrrolo[3,2-B]Pyridine in high-purity grades suitable for research and development. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and MS are available upon request. We adhere to cGMP principles for manufacturing and quality management where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.