Description

3-Chloro-6-Azaindole-4-Carboxylic Acid is a high-purity, heterocyclic carboxylic acid building block of significant importance in modern pharmaceutical and agrochemical research. Its core value lies in its versatile chemical structure, which serves as a critical scaffold for synthesizing novel, biologically active compounds. This intermediate is essential for medicinal chemists and process development scientists working in drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of kinase inhibitors and other small molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in developing advanced active ingredients for crop protection products.
• Chemical Biology: Serves as a versatile scaffold for creating molecular probes and tool compounds to study biological processes.
• Organic Synthesis: Employed in constructing complex heterocyclic systems for material science and specialty chemical applications.
• Contract Research & Development (CRO/CMO): Supplied to research organizations for custom synthesis and library production.

Basic Information

Product Name	3-Chloro-6-Azaindole-4-Carboxylic Acid
CAS No.	1190320-29-6
Molecular Formula	C8H5ClN2O2
Molecular Weight	196.59 g/mol
Synonyms	3-Chloro-1H-pyrrolo[2,3-b]pyridine-4-carboxylic acid; 3-Chloro-4-carboxy-6-azaindole; 3-Chloro-4-carboxy-1H-pyrrolo[2,3-b]pyridine; 3-Chloro-1H-pyrrolo[2,3-b]pyridine-4-carboxylic acid; 6-Azaindole-4-carboxylic acid, 3-chloro- derivative; 3-Chloro-6-aza-indole-4-carboxylic acid; 3-Chloro-4-carboxy-6-aza-indole; 3-Chloro-1H-6-azaindole-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Chloro-6-Azaindole-4-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all relevant specifications. We support development and commercial projects with material produced to meet GMP and ICH Q7 guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.