Description

3-Iodo-7-(Trifluoromethyl)-4-Azaindole is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. Its unique structure, combining an iodine substituent with a trifluoromethyl group on an azaindole scaffold, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, drug discovery, and the development of novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of potential drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the azaindole core.
• Material Science: Serves as a precursor for organic electronic materials and functional dyes due to its electron-deficient character.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and library synthesis for hit-to-lead optimization.
• Chemical Biology: Used as a probe or labeling agent in biochemical assays, capitalizing on the reactivity of the iodine atom.
• Academic & Contract Research: A valuable reagent for methodological development and novel heterocycle synthesis in academic and CRO laboratories.

Basic Information

Product Name	3-Iodo-7-(Trifluoromethyl)-4-Azaindole
CAS No.	1190316-38-1
Molecular Formula	C8H4F3IN2
Molecular Weight	312.03 g/mol
Synonyms	7-(Trifluoromethyl)-3-iodo-1H-pyrrolo[2,3-b]pyridine; 3-Iodo-7-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine; 3-Iodo-7-(trifluoromethyl)-4-azaindole; 1H-Pyrrolo[2,3-b]pyridine, 3-iodo-7-(trifluoromethyl)-; 3-Iodo-7-trifluoromethyl-1H-pyrrolo[2,3-b]pyridine; 3-Iodo-7-trifluoromethyl-4-azaindole; Azaindole derivative CAS 1190316-38-1
EINECS	Contact for details

Quality Control

Every batch of 3-Iodo-7-(Trifluoromethyl)-4-Azaindole is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.