Description

7-Fluoro-5-Azaindole-3-Carboxaldehyde is a high-value, fluorinated heterocyclic building block essential for modern pharmaceutical and agrochemical research. Its core value lies in its unique molecular scaffold, which combines a reactive aldehyde group with a fluorinated azaindole system, enabling the synthesis of novel compounds with enhanced biological activity and metabolic stability. This intermediate is critically needed by R&D chemists and process development scientists in the pharmaceutical industry for constructing targeted libraries and developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, particularly for oncology and anti-inflammatory drug discovery programs.
• Agrochemical Research: Used in developing novel herbicides and fungicides, where the fluorine atom can improve lipophilicity and environmental persistence.
• Chemical Biology Probes: Serves as a versatile handle for creating fluorescent tags or affinity probes to study protein-ligand interactions.
• Material Science: Potential building block for advanced organic electronic materials due to its electron-deficient heterocyclic core.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and clinical trial materials.

Basic Information

Product Name	7-Fluoro-5-Azaindole-3-Carboxaldehyde
CAS No.	1190315-32-2
Molecular Formula	C8H5FN2O
Molecular Weight	164.14 g/mol
Synonyms	7-Fluoro-1H-pyrrolo[3,2-b]pyridine-3-carboxaldehyde; 7-Fluoro-5-azaindole-3-carbaldehyde; 3-Formyl-7-fluoro-5-azaindole; 7-Fluoro-1H-pyrrolo[3,2-b]pyridine-3-carbaldehyde; 7-Fluoro-5-aza-indole-3-carboxaldehyde; 7-Fluoro-1H-pyrrolo[3,2-b]pyridine-3-carboxaldehyde; 7-Fluoro-5-azaindol-3-ylcarboxaldehyde
EINECS	Contact for details

Quality Control

Our 7-Fluoro-5-Azaindole-3-Carboxaldehyde is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable and ensure compliance with global regulatory frameworks, including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.