Description

2-Oxo-1H,2H,3H-Pyrrolo[2,3-B]Pyridine-4-Carbonitrile is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1190313-69-9. This heterocyclic nitrile compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), valued for its precise molecular architecture. It is essential for research and development chemists and manufacturers in the pharmaceutical and agrochemical industries seeking to develop novel therapeutic agents and specialty chemicals.

Application

This specialized intermediate serves as a key precursor in several high-value synthetic pathways.

• Pharmaceutical Intermediate: Core building block for the synthesis of novel small molecule drugs, particularly in kinase inhibitor research.
• Agrochemical Synthesis: Used in the development of new-generation pesticides and herbicides with targeted modes of action.
• Organic Light-Emitting Diode (OLED) Materials: Potential precursor for electron-transport or emissive layer materials in display technology.
• Ligand Synthesis for Catalysis: Serves as a scaffold for creating novel ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Academic & Contract Research: Vital reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.
• Fluorescent Probe Development: Utilized in the design of molecular probes and sensors for biochemical imaging and diagnostics.

Basic Information

Item	Details
Product Name	2-Oxo-1H,2H,3H-Pyrrolo[2,3-B]Pyridine-4-Carbonitrile
CAS No.	1190313-69-9
Molecular Formula	C9H7N3O
Molecular Weight	173.17 g/mol
Synonyms	4-Cyano-2-oxo-1,2,3,4-tetrahydropyrrolo[2,3-b]pyridine; 1,2,3,4-Tetrahydropyrrolo[2,3-b]pyridine-4-carbonitrile, 2-oxo-; Pyrrolo[2,3-b]pyridine-4-carbonitrile, 1,2,3,4-tetrahydro-2-oxo-; 2-Oxo-1,2,3,4-tetrahydropyrrolo[2,3-b]pyridine-4-carbonitrile; 1190313-69-9; 4-CN-2-oxo-THP; 2-Oxo-THP-4-carbonitrile
EINECS	Contact for details

Quality Control

Our production of 2-Oxo-1H,2H,3H-Pyrrolo[2,3-B]Pyridine-4-Carbonitrile adheres to stringent quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.