Description

3-Nitro-6-Trifluoromethyl-4-Azaindole is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic combination of a nitro group and a trifluoromethyl group on an azaindole scaffold, enabling precise molecular modifications for enhanced bioactivity and physicochemical properties. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioisosteric properties of the trifluoromethyl group.
• Chemical Biology Probe: Serves as a versatile scaffold for constructing molecular probes to study enzyme function and biological pathways.
• Material Science Research: Investigated as a building block for advanced organic electronic materials due to its electron-deficient aromatic system.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	3-Nitro-6-Trifluoromethyl-4-Azaindole
CAS No.	1190311-72-8
Molecular Formula	C8H4F3N3O2
Molecular Weight	231.14 g/mol
Synonyms	6-(Trifluoromethyl)-3-nitro-1H-pyrrolo[3,2-c]pyridine; 3-Nitro-6-(trifluoromethyl)-1H-pyrrolo[3,2-c]pyridine; 1H-Pyrrolo[3,2-c]pyridine, 3-nitro-6-(trifluoromethyl)-; 3-Nitro-6-trifluoromethyl-1H-pyrrolo[3,2-c]pyridine; 3-Nitro-6-trifluoromethyl-4-aza-indole
EINECS	Contact for details

Quality Control

Our 3-Nitro-6-Trifluoromethyl-4-Azaindole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. For custom synthesis projects, we adhere to cGMP guidelines as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to brown powder or crystalline solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.