Description

1H-Pyrrolo[3,2-C]Pyridine, 4-(Trifluoromethyl)- is a high-value pharmaceutical intermediate and advanced building block. This heterocyclic compound is prized for its unique molecular scaffold, which incorporates a trifluoromethyl group—a key motif known to enhance the metabolic stability, lipophilicity, and bioavailability of active molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical building block for the research and synthesis of new active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and antiviral therapeutic areas.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve efficacy and environmental profile.
• Material Science Precursor: Serves as a specialized monomer or precursor for advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) or conductive polymers.
• Chemical Biology Probe: Employed in medicinal chemistry and chemical biology for structure-activity relationship (SAR) studies and as a probe molecule in biochemical assays.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up services.

Basic Information

Product Name	1H-Pyrrolo[3,2-C]Pyridine, 4-(Trifluoromethyl)-
CAS No.	1190309-89-7
Molecular Formula	C8H5F3N2
Molecular Weight	186.14 g/mol
Synonyms	4-(Trifluoromethyl)-1H-pyrrolo[3,2-c]pyridine; 4-Trifluoromethyl-1H-pyrrolo[3,2-c]pyridine; 1H-Pyrrolo[3,2-c]pyridine, 4-(trifluoromethyl)-; 4-(Trifluoromethyl)pyrrolo[3,2-c]pyridine; Pyrrolo[3,2-c]pyridine, 4-(trifluoromethyl)-; 1190309-89-7; 4-CF3-1H-pyrrolo[3,2-c]pyridine
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[3,2-C]Pyridine, 4-(Trifluoromethyl)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.