Description

3-Bromo-1H-Pyrrolo[2,3-B]Pyridine-5-Carbonitrile is a high-value brominated heterocyclic building block essential for modern pharmaceutical and agrochemical research. This compound serves as a critical intermediate in the synthesis of complex molecules, enabling the exploration of novel biological activities. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing advanced scaffolds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, particularly in oncology and anti-inflammatory drug discovery programs.
• Agrochemical Research: Used in the synthesis of novel active ingredients for crop protection, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a precursor for organic electronic materials and functional dyes due to its electron-deficient pyrrolopyridine structure.
• Chemical Biology: Employed as a molecular probe or a tagging reagent in bioconjugation and proteomics research.
• Academic Research: Utilized in methodological studies for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and heterocyclic chemistry.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs for client-specific molecule assembly.

Basic Information

Product Name	3-Bromo-1H-Pyrrolo[2,3-B]Pyridine-5-Carbonitrile
CAS No.	1190309-69-3
Molecular Formula	C8H4BrN3
Molecular Weight	222.04 g/mol
Synonyms	3-Bromo-1H-pyrrolo[2,3-b]pyridine-5-carbonitrile; 5-Cyano-3-bromo-1H-pyrrolo[2,3-b]pyridine; 3-Bromo-5-cyano-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine-5-carbonitrile, 3-bromo-; 3-Bromo-1H-7-azaindole-5-carbonitrile; 3-Bromo-5-cyanopyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-1H-Pyrrolo[2,3-B]Pyridine-5-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed and may require storage under an inert atmosphere for long-term preservation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Impurity (HPLC)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.