Description

4-(3-Chloro-4-Fluorophenyl)-4,5,6,7-Tetrahydro-3H-Imidazo[4,5-C]Pyridine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular scaffolds. Pharmaceutical R&D teams and fine chemical manufacturers need it to develop next-generation drug candidates targeting complex diseases, where its specific halogenated phenyl and fused imidazopyridine system offers unique pharmacophoric properties. The CAS number for this compound is provided separately in the table below.

Application

• Pharmaceutical Intermediate: Primary use as a sophisticated building block for the research and development of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).
• Kinase Inhibitor Synthesis: Core scaffold in the development of small molecule kinase inhibitors for oncology and inflammatory disease applications.
• Medicinal Chemistry Research: Valuable precursor for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Preclinical Candidate Development: Used in the scale-up synthesis of compounds for preclinical toxicology and pharmacology studies.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs and CROs for custom synthesis and process development projects.
• Chemical Biology Probes: Potential use in the creation of specialized molecular probes for target identification and validation.

Basic Information

Product Name	4-(3-Chloro-4-Fluorophenyl)-4,5,6,7-Tetrahydro-3H-Imidazo[4,5-C]Pyridine
CAS No.	1189749-85-6
Molecular Formula	C12H11ClFN3
Molecular Weight	251.69 g/mol
Synonyms	4-(3-Chloro-4-fluorophenyl)-3H,4H,5H,6H,7H-imidazo[4,5-c]pyridine; 4-(3-Chloro-4-fluorophenyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine; 1189749-85-6; 4-(3-Chloro-4-fluorophenyl)-4,5,6,7-tetrahydroimidazo[4,5-c]pyridine; 4-(3-Chloro-4-fluorophenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine; 4-(3-Chloro-4-fluorophenyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine; 4-(3-Chloro-4-fluorophenyl)-4,5,6,7-tetrahydroimidazo[4,5-c]pyridine hydrochloride (salt form); 3H-Imidazo[4,5-c]pyridine, 4-(3-chloro-4-fluorophenyl)-4,5,6,7-tetrahydro-
EINECS	Contact for details

Quality Control

Our production of 4-(3-Chloro-4-Fluorophenyl)-4,5,6,7-Tetrahydro-3H-Imidazo[4,5-C]Pyridine adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and rigorous control of residual solvents and impurities. We provide detailed Certificates of Analysis (COA) with each shipment, ensuring traceability and compliance with customer specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.