Description

Ho-Peg14-Oh CAS NO 1189112-05-7 is a high-purity, monodisperse polyethylene glycol (PEG) derivative featuring a hydroxyl group at each terminus. This bifunctional PEG linker is essential for creating stable, hydrophilic spacers in bioconjugation and advanced material synthesis. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for developing drug delivery systems, diagnostic reagents, and functional polymers.

Application

• Bioconjugation Linker: Used to conjugate peptides, proteins, or antibodies to drugs, surfaces, or other biomolecules to improve solubility and stability.
• Drug Delivery Systems: Serves as a key component in the synthesis of PEGylated therapeutics, liposomes, and nanoparticles to enhance pharmacokinetics.
• Diagnostic Reagents: Employed in the development of assay components and contrast agents where controlled spacing and hydrophilicity are required.
• Polymer Chemistry: Acts as a macroinitiator or building block for creating functional, biocompatible hydrogels and block copolymers.
• Surface Modification: Used to create non-fouling, hydrophilic coatings on medical devices and sensor surfaces.
• Cross-linking Agent: Functions as a hydrophilic cross-linker in the preparation of biodegradable matrices for tissue engineering.

Basic Information

Product Name	Ho-Peg14-Oh
CAS No.	1189112-05-7
Molecular Formula	C28H58O15
Molecular Weight	634.75 g/mol
Synonyms	1,14-Bis(hydroxy)tetraethylene glycol; α,ω-Dihydroxytetradecaethylene glycol; Tetraethylene glycol, 1,14-dihydroxy-; HO-PEG14-OH; 14-Mer PEG diol; Poly(ethylene glycol) diol (MW ~600); PEG 600 diol; 2,2'-(Ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl) bis(oxy)diethanol
EINECS	Contact for details

Quality Control

Our Ho-Peg14-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent molecular weight distribution. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under desiccant. This product is hygroscopic (moisture-sensitive). Allow the sealed container to reach room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white waxy solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Molecular Weight (GPC)	600 ± 50 Da
Polydispersity Index (PDI)	≤ 1.05
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.