Description

tert-Butyl (2-(Trimethylsilyl)Furo[3,2-B]Pyridin-6-Yl)Methylcarbamate is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is critical for enabling complex synthetic routes in modern medicinal chemistry, offering a protected amine functionality and a silyl-protected furanopyridine scaffold. It is primarily utilized by research and development teams in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs) and investigational compounds.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities with potential therapeutic value.
• Process Chemistry Development: Employed in the scale-up and route scouting for the commercial production of new APIs, leveraging its stable protective groups.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) engaged in synthetic organic chemistry and heterocyclic compound research.
• Precursor for Functionalized Heterocycles: The trimethylsilyl and Boc-protected groups allow for selective deprotection and further functionalization, enabling the creation of diverse molecular libraries.

Basic Information

Product Name	tert-Butyl (2-(Trimethylsilyl)Furo[3,2-B]Pyridin-6-Yl)Methylcarbamate
CAS No.	1188996-58-8
Molecular Formula	C17H26N2O3Si
Molecular Weight	334.49 g/mol
Synonyms	Boc-6-(aminomethyl)-2-(trimethylsilyl)furo[3,2-b]pyridine; tert-Butyl N-[[2-(trimethylsilyl)furo[3,2-b]pyridin-6-yl]methyl]carbamate; 2-(Trimethylsilyl)-6-((tert-butoxycarbonylamino)methyl)furo[3,2-b]pyridine; (2-(Trimethylsilyl)furo[3,2-b]pyridin-6-yl)methylcarbamic acid tert-butyl ester; 6-((Boc-amino)methyl)-2-TMS-furo[3,2-b]pyridine; N-Boc-2-TMS-furo[3,2-b]pyridine-6-methylamine
EINECS	Contact for details

Quality Control

Our production of tert-Butyl (2-(Trimethylsilyl)Furo[3,2-B]Pyridin-6-Yl)Methylcarbamate adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements or internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.