Description

2-Hydroxy-3-Pyridinecarboximidamide Hydrochloride is a high-purity chemical intermediate of significant importance in modern synthetic organic chemistry. This compound is valued for its role as a versatile building block in the development of complex heterocyclic molecules, particularly in pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its pyridine-based heterocyclic structure.
• Ligand Synthesis: Serves as a starting material for creating complex chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, dyes, and advanced functional materials.
• Academic & Institutional R&D: Utilized in university and government laboratories for fundamental research in heterocyclic and medicinal chemistry.
• Building Block for Bioactive Molecules: Integral for constructing molecules with potential biological activity, including kinase inhibitors and receptor modulators.

Basic Information

Item	Details
Product Name	2-Hydroxy-3-Pyridinecarboximidamide Hydrochloride
CAS No.	1188964-88-6
Molecular Formula	C6H8N3O·HCl
Molecular Weight	189.61 g/mol
Synonyms	3-Amidino-2-pyridinol Hydrochloride; 2-Hydroxynicotinamidine Hydrochloride; 2-Pyridinol-3-carboximidamide Hydrochloride; 3-Cyano-2-hydroxypyridine Amidine Hydrochloride; 2-Hydroxy-3-pyridinecarboximidamide Monohydrochloride; 3-(Aminoiminomethyl)-2-pyridinol Hydrochloride; 2-Hydroxypyridine-3-carboximidamide HCl
EINECS	Contact for details

Quality Control

Every batch of 2-Hydroxy-3-Pyridinecarboximidamide Hydrochloride is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We ensure compliance with rigorous internal specifications, which are aligned with industry best practices for fine chemical intermediates. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.