Description

tert-Butyl5-Bromopyridin-2-Yl(Methyl)Carbamate is a high-purity, advanced pharmaceutical intermediate characterized by its bromopyridine and carbamate functional groups. This compound is of significant value for its role as a versatile building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel drug candidates and active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Synthesis: Serves as a building block for developing novel crop protection agents and pesticides.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.

Basic Information

Product Name	tert-Butyl5-Bromopyridin-2-Yl(Methyl)Carbamate
CAS No.	1188477-11-3
Molecular Formula	C11H15BrN2O2
Molecular Weight	287.15 g/mol
Synonyms	tert-Butyl (5-bromopyridin-2-yl)(methyl)carbamate; 5-Bromo-N-methyl-N-(pyridin-2-yl)carbamic acid tert-butyl ester; 2-[(tert-Butoxycarbonyl)(methyl)amino]-5-bromopyridine; Carbamic acid, N-(5-bromo-2-pyridinyl)-N-methyl-, 1,1-dimethylethyl ester; tert-Butyl methyl(5-bromopyridin-2-yl)carbamate; 1188477-11-3; BOC-Protected 5-Bromo-2-(Methylamino)pyridine
EINECS	Contact for details

Quality Control

Our tert-Butyl5-Bromopyridin-2-Yl(Methyl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee supply reliability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This material is light-sensitive (store away from light). Keep container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.