Description

tert-Butyl 1-Bromo-5,6-Dihydroimidazo[1,5-A]Pyrazine-7(8H)-Carboxylate is a high-value, advanced pharmaceutical intermediate featuring a reactive bromine atom on a fused imidazopyrazine scaffold. This compound matters for its critical role as a versatile building block in modern medicinal chemistry, enabling the synthesis of complex molecules with potential therapeutic applications. Pharmaceutical R&D and fine chemical synthesis teams need it for constructing novel drug candidates, particularly in the development of kinase inhibitors and other targeted small-molecule therapies.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Kinase Inhibitor Synthesis: Serves as a core scaffold or precursor in the development of targeted kinase inhibitors for oncology and inflammatory diseases.
• Peptidomimetic Chemistry: Employed in the design and synthesis of peptidomimetics and other bioactive heterocyclic compounds.
• Chemical Biology Probes: Useful for creating tool compounds and probes to study biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for custom synthesis projects and scale-up activities.

Basic Information

Item	Details
Product Name	tert-Butyl 1-Bromo-5,6-Dihydroimidazo[1,5-A]Pyrazine-7(8H)-Carboxylate
CAS No.	1188265-64-6
Molecular Formula	C11H16BrN3O2
Molecular Weight	302.17 g/mol
Synonyms	1-Bromo-7-(tert-butoxycarbonyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine; tert-Butyl 1-bromo-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine-7-carboxylate; 7-Boc-1-bromo-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine; 1-Bromo-7-Boc-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine; 1-Bromo-5,6-dihydroimidazo[1,5-a]pyrazine-7(8H)-carboxylic acid tert-butyl ester; Boc-Protected 1-Bromo-tetrahydroimidazopyrazine
EINECS	Contact for details

Quality Control

Our tert-Butyl 1-Bromo-5,6-Dihydroimidazo[1,5-A]Pyrazine-7(8H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.