Description

Dihydroisoferulic Acid 3-o-Glucuronide is a specific glucuronide conjugate of dihydroisoferulic acid, a key metabolite in the study of phenolic acid metabolism. This compound is of significant interest for research and development in the fields of pharmacology and nutraceuticals, where understanding metabolic pathways and bioavailability is crucial. It serves as a vital reference standard and intermediate for analytical laboratories, pharmaceutical developers, and academic institutions focused on pharmacokinetics, biomarker discovery, and the bioactivity of plant-derived phenolics.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of dihydroisoferulic acid metabolites in drug development and pharmacokinetic studies.
• Biomarker Research: Serves as a critical standard in clinical and nutritional studies to identify and quantify phase II metabolites in biological samples (e.g., plasma, urine).
• Metabolic Pathway Investigation: Essential for in-vitro and in-vivo research to elucidate the conjugation and excretion pathways of dietary phenolic acids.
• Nutraceutical & Functional Food R&D: Employed in studies assessing the bioavailability, absorption, and health benefits of complex plant extracts and their metabolites.
• Analytical Method Development: Used as a high-purity calibrant for developing and validating advanced analytical methods such as LC-MS/MS and HPLC.
• Enzyme Activity Assays: Acts as a substrate or product in assays studying the activity of UDP-glucuronosyltransferase (UGT) enzymes.

Basic Information

Item	Detail
Product Name	Dihydroisoferulic Acid 3-o-Glucuronide
CAS No.	1187945-72-7
Molecular Formula	C16H20O11
Molecular Weight	388.32 g/mol
Synonyms	3-[(3-Hydroxy-4-methoxyphenyl)propionyl]glucuronide; Dihydroferulic Acid 3-O-Glucuronide; 3-Hydroxy-4-methoxyhydrocinnamic Acid 3-O-β-D-Glucuronide; 3-(3-Hydroxy-4-methoxyphenyl)propanoic Acid 3-O-β-D-Glucopyranosiduronic Acid; Dihydroisoferulic Acid β-D-Glucuronide; Isoferulic Acid Dihydro Derivative Glucuronide
EINECS	Contact for details

Quality Control

Every batch of Dihydroisoferulic Acid 3-o-Glucuronide is manufactured under strict quality management systems. Our products undergo rigorous identity, purity, and impurity profile testing using advanced chromatographic and spectroscopic techniques to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and chromatographic data is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.