Description

2-(5-Trifluoromethyl-Pyridin-2-Yl)-Ethylamine Dihydrochloride is a high-purity, advanced pharmaceutical intermediate and building block of significant commercial interest. This compound is valued for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily sought by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging the biological activity of the pyridine and trifluoromethyl motifs.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Process Chemistry Development: Used by CDMOs for scaling up synthetic routes from laboratory to pilot and commercial production.
• Academic & Industrial R&D: A versatile reagent for methodological development in organic synthesis and medicinal chemistry programs.

Basic Information

Product Name	2-(5-Trifluoromethyl-Pyridin-2-Yl)-Ethylamine Dihydrochloride
CAS No.	1187932-37-1
Molecular Formula	C8H9Cl2F3N2
Molecular Weight	261.07 g/mol
Synonyms	2-(5-(Trifluoromethyl)pyridin-2-yl)ethan-1-amine dihydrochloride; 2-[5-(Trifluoromethyl)-2-pyridinyl]ethylamine dihydrochloride; 2-(5-Trifluoromethyl-2-pyridyl)ethylamine hydrochloride (1:2); 2-(5-Trifluoromethylpyridin-2-yl)ethanamine dihydrochloride; 2-(5-Trifluoromethyl-2-pyridinyl)ethylamine dihydrochloride; 2-(5-Trifluoromethylpyridin-2-yl)ethylammonium chloride
EINECS	Contact for details

Quality Control

Our 2-(5-Trifluoromethyl-Pyridin-2-Yl)-Ethylamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert conditions (e.g., nitrogen atmosphere) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.