Description

1-(4-Chloro-Pyridin-2-Yl)-Piperazine Dihydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS number 1187932-16-6. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and antiviral therapeutics. It is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in novel drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting neurological pathways.
• Active Pharmaceutical Ingredient (API) Development: Used in research and development for creating new candidate compounds with potential therapeutic effects.
• Chemical Synthesis Research: Serves as a versatile building block in academic and industrial laboratories for constructing novel heterocyclic compounds.
• Process Chemistry & Scale-Up: Employed in optimizing synthetic routes from laboratory scale to pilot and commercial manufacturing.
• Reference Standard: Used as a high-purity standard for analytical method development and quality control in pharmaceutical analysis.

Basic Information

Item	Detail
Product Name	1-(4-Chloro-Pyridin-2-Yl)-Piperazine Dihydrochloride
CAS No.	1187932-16-6
Molecular Formula	C9H13ClN3·2HCl
Molecular Weight	284.04 g/mol
Synonyms	1-(4-Chloropyridin-2-yl)piperazine dihydrochloride; 2-(4-Chloro-2-pyridinyl)-1-piperazine dihydrochloride; 4-Chloro-2-(piperazin-1-yl)pyridine dihydrochloride; 1-(4-Chloro-2-pyridinyl)piperazine dihydrochloride; 1187932-16-6; 4-Chloro-2-piperazin-1-ylpyridine dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-(4-Chloro-Pyridin-2-Yl)-Piperazine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identity confirmation via spectroscopic methods. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.