Description

(S)-3-Methyl-1-(Tetrahydro-Pyran-4-Yl)-Piperazine is a chiral piperazine derivative of significant importance in modern pharmaceutical research and development. This compound serves as a versatile and high-value building block for the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought after by research organizations and pharmaceutical manufacturers engaged in the discovery and production of novel therapeutics, particularly those targeting the central nervous system and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates.
• Active Pharmaceutical Ingredient (API) Development: Used as a core structural moiety in the design and manufacture of new chemical entities.
• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand in stereoselective catalytic reactions.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Preclinical & Clinical Trial Material: Sourced for the production of materials required for non-clinical and clinical development stages.
• Chemical Reference Standard: Used as an analytical standard for quality control and method development.

Basic Information

Item	Detail
Product Name	(S)-3-Methyl-1-(Tetrahydro-Pyran-4-Yl)-Piperazine
CAS No.	1187931-31-2
Molecular Formula	C10H20N2O
Molecular Weight	184.28 g/mol
Synonyms	(S)-3-Methyl-1-(Tetrahydro-2H-pyran-4-yl)piperazine; (S)-3-Methyl-1-(oxan-4-yl)piperazine; (S)-1-(Tetrahydro-2H-pyran-4-yl)-3-methylpiperazine; (S)-3-Methyl-1-(tetrahydropyran-4-yl)piperazine; (3S)-3-Methyl-1-(oxan-4-yl)piperazine; (S)-1-(THP-4-yl)-3-methylpiperazine; 1187931-31-2
EINECS	Contact for details

Quality Control

Our (S)-3-Methyl-1-(Tetrahydro-Pyran-4-Yl)-Piperazine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. All batches are supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.