Description

(R)-3-Methyl-1-(Tetrahydro-Pyran-4-Yl)-Piperazine is a high-purity chiral piperazine derivative of significant importance in modern pharmaceutical research and development. This compound serves as a critical chiral building block and intermediate for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily needed by pharmaceutical companies, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of central nervous system (CNS) agents, receptor modulators, and other therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly for CNS disorders.
• Asymmetric Synthesis: Used as a chiral ligand or auxiliary in catalytic asymmetric reactions to induce stereoselectivity.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization for new molecular entities.
• API Development: Serves as a core structural component in the development of potential APIs targeting specific receptors.
• Chemical Biology: Utilized in the design and synthesis of molecular probes for studying biological pathways.
• Fine Chemical Production: An important intermediate for the custom synthesis of complex, high-value specialty chemicals.

Basic Information

Item	Detail
Product Name	(R)-3-Methyl-1-(Tetrahydro-Pyran-4-Yl)-Piperazine
CAS No.	1187931-25-4
Molecular Formula	C10H20N2O
Molecular Weight	184.28 g/mol
Synonyms	(R)-3-Methyl-1-(Oxan-4-yl)piperazine; (R)-3-Methyl-1-(Tetrahydropyran-4-yl)piperazine; (R)-1-(Tetrahydro-2H-pyran-4-yl)-3-methylpiperazine; (R)-MTP; (R)-3-Methyl-1-(4-tetrahydropyranyl)piperazine; (R)-enantiomer of 3-Methyl-1-(tetrahydropyran-4-yl)piperazine
EINECS	Contact for details

Quality Control

Our (R)-3-Methyl-1-(Tetrahydro-Pyran-4-Yl)-Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-grade standards suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.