Description

5-Bromo-3-Methyl-2-(2,2,2-Trifluoroethoxy)Pyridine is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated and fluorinated ether side chain. This compound matters for its critical role as a versatile building block in modern medicinal chemistry, enabling the synthesis of complex molecules with enhanced biological activity and metabolic stability. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients, particularly in areas such as kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the biological activity of the pyridine and trifluoroethoxy motifs.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to the reactive bromine substituent.
• Material Science: Potential use in the synthesis of specialty chemicals and functional materials requiring fluorinated aromatic components.
• Contract Research & Development (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for client projects.

Basic Information

Product Name	5-Bromo-3-Methyl-2-(2,2,2-Trifluoroethoxy)Pyridine
CAS No.	1187930-58-0
Molecular Formula	C9H7BrF3NO
Molecular Weight	282.06 g/mol
Synonyms	2-(2,2,2-Trifluoroethoxy)-5-bromo-3-methylpyridine; 5-Bromo-3-methyl-2-(2,2,2-trifluoroethoxy)pyridine; 5-Bromo-3-methyl-2-(trifluoroethoxy)pyridine; Pyridine, 5-bromo-3-methyl-2-(2,2,2-trifluoroethoxy)-; 1187930-58-0
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Methyl-2-(2,2,2-Trifluoroethoxy)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards where applicable, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong acids, bases, and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.