Description

(S)-1-Cbz-3-Isopropyl-Piperazine is a high-purity chiral piperazine derivative, serving as a critical building block in modern pharmaceutical synthesis. Its value lies in providing a stereochemically defined scaffold for constructing complex molecules with targeted biological activity. This advanced intermediate is essential for research and development chemists in the pharmaceutical and biotechnology industries, particularly for creating novel active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Asymmetric Synthesis: Utilized in the construction of complex, stereochemically pure molecules for medicinal chemistry and process research.
• Peptidomimetic Chemistry: Serves as a constrained scaffold in the design of peptide analogs to improve metabolic stability and bioavailability.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands used in asymmetric catalysis and metal complexation.
• Chemical Biology Research: Employed in the synthesis of molecular probes and tool compounds for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up activities under GMP or non-GMP conditions.

Basic Information

Product Name	(S)-1-Cbz-3-Isopropyl-Piperazine
CAS No.	1187930-14-8
Molecular Formula	C15H22N2O2
Molecular Weight	262.35 g/mol
Synonyms	(S)-1-(Benzyloxycarbonyl)-3-(propan-2-yl)piperazine; (S)-1-Carbobenzoxy-3-isopropylpiperazine; (S)-3-Isopropyl-1-[(phenylmethoxy)carbonyl]piperazine; (S)-N-Cbz-3-isopropylpiperazine; (S)-1-Cbz-3-(1-methylethyl)piperazine; (S)-1-(Benzyloxycarbonyl)-3-isopropylpiperazine; (S)-Cbz-3-iPr-piperazine
EINECS	Contact for details

Quality Control

Our (S)-1-Cbz-3-Isopropyl-Piperazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to meet the stringent requirements of pharmaceutical R&D. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.