Description

1-Boc-Piperidine-4-Carboxamidine Oxalate is a high-purity, protected amidine derivative used as a critical building block in organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists working on protease inhibitors, kinase inhibitors, and other bioactive molecules where a rigid, functionalized piperidine scaffold is required.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of small molecule drug candidates, particularly those targeting enzymatic pathways.
• Protease Inhibitor Development: Used to construct the pharmacophore core for inhibitors of serine, cysteine, or aspartic proteases.
• Kinase Inhibitor Research: Serves as a versatile scaffold for developing selective kinase inhibitors in oncology and inflammatory disease research.
• Chemical Biology Probes: Employed in the creation of activity-based probes (ABPs) or photoaffinity labels to study enzyme function and target engagement.
• Peptidomimetic Synthesis: Facilitates the development of peptidomimetics by providing a stable, non-peptide backbone with amidine functionality.
• Agrochemical Research: Potential intermediate in the development of novel active ingredients for crop protection.

Basic Information

Product Name	1-Boc-Piperidine-4-Carboxamidine Oxalate
CAS No.	1187929-57-2
Molecular Formula	C12H21N3O5
Molecular Weight	287.31 g/mol
Synonyms	1-Boc-4-Carbamimidoylpiperidine Oxalate; tert-Butyl 4-(carbamimidoyl)piperidine-1-carboxylate Oxalate; 4-(Aminoiminomethyl)-1-piperidinecarboxylic Acid 1,1-Dimethylethyl Ester Oxalate; 1-(tert-Butoxycarbonyl)piperidine-4-carboxamidine Oxalate; N-Boc-4-Piperidinecarboxamidine Oxalate; 1-Boc-4-Piperidinecarboxamidine Oxalate; Piperidine-4-carboxamidine, 1-(1,1-dimethylethoxy)carbonyl-, oxalate (1:1)
EINECS	Contact for details

Quality Control

Our 1-Boc-Piperidine-4-Carboxamidine Oxalate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and consistency, meeting the stringent requirements for research and development use. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.