Description

1-[4-(Pyridin-4-Ylmethoxy)-Phenyl]-Piperazine Trihydrochloride is a high-purity, non-natural amino acid derivative and a key pharmaceutical intermediate. Its value lies in its role as a sophisticated building block for the synthesis of complex bioactive molecules, particularly in medicinal chemistry research and development. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for developing new therapeutic agents.
• Bioconjugation & Probe Development: Serves as a linker or functional group for creating biochemical probes and diagnostic agents.
• Library Synthesis: Employed in combinatorial chemistry for generating diverse compound libraries for high-throughput screening.
• Chemical Biology Studies: Utilized to modify peptides or proteins to study biological pathways and protein function.
• Reference Standard: Acts as a certified reference material (CRM) for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	1-[4-(Pyridin-4-Ylmethoxy)-Phenyl]-Piperazine Trihydrochloride
CAS No.	1187929-05-0
Molecular Formula	C16H20N3O•3HCl
Molecular Weight	398.73 g/mol
Synonyms	1-[4-[(Pyridin-4-yl)methoxy]phenyl]piperazine trihydrochloride; 4-[(4-Piperazin-1-ylphenoxy)methyl]pyridine trihydrochloride; 1-(4-((Pyridin-4-yl)methoxy)phenyl)piperazine trihydrochloride; 1-[4-(4-Pyridylmethoxy)phenyl]piperazine trihydrochloride; 1-(4-(Pyridin-4-ylmethoxy)phenyl)piperazine hydrochloride (3:1); Piperazine, 1-[4-[(4-pyridinyl)methoxy]phenyl]-, trihydrochloride
EINECS	Contact for details

Quality Control

Our 1-[4-(Pyridin-4-Ylmethoxy)-Phenyl]-Piperazine Trihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.