Description

3-Nitro-5,6,7,8-Tetrahydro-[1,6]Naphthyridine Dihydrochloride is a high-purity, heterocyclic organic compound primarily utilized as a critical pharmaceutical intermediate. Its value lies in its role as a sophisticated building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex nitrogen-containing scaffolds. This compound is essential for research and development chemists and process scale-up teams in the pharmaceutical, agrochemical, and advanced material sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry programs, enabling the exploration of new structure-activity relationships (SAR).
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides that require specific heterocyclic frameworks for bioactivity.
• Material Science: Potential building block for creating specialized ligands, catalysts, or organic electronic materials due to its nitro and dihydrochloride functional groups.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis and scale-up projects.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Item	Details
Product Name	3-Nitro-5,6,7,8-Tetrahydro-[1,6]Naphthyridine Dihydrochloride
CAS No.	1187928-81-9
Molecular Formula	C8H11Cl2N3O2
Molecular Weight	252.10 g/mol
Synonyms	3-Nitro-5,6,7,8-tetrahydro-1,6-naphthyridine dihydrochloride; 1,6-Naphthyridine, 3-nitro-5,6,7,8-tetrahydro-, dihydrochloride; 5,6,7,8-Tetrahydro-3-nitro-[1,6]naphthyridine dihydrochloride; 3-Nitro-5,6,7,8-tetrahydro-1,6-naphthyridine HCl salt; 1187928-81-9; 3-Nitro-5,6,7,8-tetrahydro[1,6]naphthyridine 2HCl
EINECS	Contact for details

Quality Control

Our 3-Nitro-5,6,7,8-Tetrahydro-[1,6]Naphthyridine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical intermediate applications. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to brownish powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.