Description

1-Isopropylpiperazin-2-One Hydrochloride is a high-purity pharmaceutical intermediate and building block of significant importance in modern organic synthesis. Its value lies in its role as a key precursor for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and other therapeutic areas. This compound is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex drug molecules and novel chemical entities.
• Drug Discovery & Medicinal Chemistry: Used in research libraries and for structure-activity relationship (SAR) studies to optimize lead compounds.
• Process Chemistry & Scale-Up: Serves as a key starting material or intermediate in the development of robust, scalable synthetic routes for API manufacturing.
• Biochemical Research: Employed as a reagent or probe in biochemical assays and pharmacological studies.
• Custom Synthesis: A versatile substrate for the custom synthesis of more complex, functionalized piperazine derivatives.

Basic Information

Product Name	1-Isopropylpiperazin-2-One Hydrochloride
CAS No.	1187928-58-0
Molecular Formula	C7H15ClN2O
Molecular Weight	178.66 g/mol
Synonyms	1-Isopropyl-2-oxopiperazine hydrochloride; 1-Isopropylpiperazin-2-one HCl; 2-Piperazinone, 1-(1-methylethyl)-, hydrochloride; 1-(Propan-2-yl)piperazin-2-one hydrochloride; 1-Isopropyl-2-ketopiperazine hydrochloride; 1-(1-Methylethyl)-2-piperazinone monohydrochloride
EINECS	Contact for details

Quality Control

Our 1-Isopropylpiperazin-2-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.