Description

5-Amino-1-Boc-3',4',5',6'-Tetrahydro-2'H-[2,4']Bipyridinyl Oxalate is a high-purity, advanced pharmaceutical intermediate featuring a protected amino group and a complex bicyclic structure. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting neurological and oncological therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Employed in the multi-step synthesis of novel active pharmaceutical ingredients, leveraging its protected amine functionality.
• Chemical Biology Probes: Serves as a building block for creating molecular probes to study biological pathways and enzyme functions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	5-Amino-1-Boc-3',4',5',6'-Tetrahydro-2'H-[2,4']Bipyridinyl Oxalate
CAS No.	1187928-22-8
Molecular Formula	C21H29N3O6
Molecular Weight	419.47 g/mol
Synonyms	1-Boc-5-Amino-3,4,5,6-tetrahydro-2H-[2,4']bipyridinyl Oxalate; tert-Butyl 5-amino-3,4,5,6-tetrahydro-2H-[2,4'-bipyridine]-1-carboxylate oxalate; 5-Amino-1-(tert-butoxycarbonyl)-1,2,3,6-tetrahydro-2,4'-bipyridinyl Oxalate; 1-Boc-5-Amino-1,2,3,6-tetrahydro-2,4'-bipyridine Oxalate; 5-Amino-1-Boc-tetrahydro-[2,4']bipyridinyl Oxalate; 5-Amino-1-Boc-3,4,5,6-tetrahydro-2H-[2,4']bipyridinyl Oxalic Acid Salt
EINECS	Contact for details

Quality Control

Our 5-Amino-1-Boc-3',4',5',6'-Tetrahydro-2'H-[2,4']Bipyridinyl Oxalate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.