Description

(R)-1-Cyclohexyl-3-Methyl-Piperazine Dihydrochloride CAS NO 1187928-07-9 is a high-purity chiral piperazine derivative supplied as a dihydrochloride salt. This compound serves as a critical pharmaceutical intermediate and chiral building block for the synthesis of active pharmaceutical ingredients (APIs) and complex organic molecules. It is essential for research and development in medicinal chemistry, particularly for organizations requiring enantiomerically pure intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key chiral building block in the synthesis of novel therapeutic agents, including central nervous system (CNS) drugs and receptor modulators.
• Asymmetric Synthesis: Used as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Medicinal Chemistry R&D: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry: Employed in the scale-up and development of robust, GMP-compliant synthetic routes for API manufacturing.
• Chemical Reference Standard: Provides a high-purity standard for analytical method development, validation, and quality control in regulatory submissions.
• Agrochemical Research: Potential intermediate in the development of enantiomerically pure agrochemicals and plant growth regulators.

Basic Information

Item	Detail
Product Name	(R)-1-Cyclohexyl-3-Methyl-Piperazine Dihydrochloride
CAS No.	1187928-07-9
Molecular Formula	C11H24Cl2N2
Molecular Weight	255.23 g/mol
Synonyms	(R)-1-Cyclohexyl-3-methylpiperazine dihydrochloride; (R)-1-Cyclohexyl-3-methylpiperazine hydrochloride (1:2); (R)-1-Cyclohexyl-3-methyl-piperazine dihydrochloride; (R)-1-Cyclohexyl-3-methylpiperazine dihydrochloride salt; (R)-CMHP dihydrochloride; (R)-1-Cyclohexyl-3-methylpiperazine 2HCl; (R)-3-Methyl-1-cyclohexylpiperazine dihydrochloride
EINECS	Contact for details

Quality Control

Our (R)-1-Cyclohexyl-3-Methyl-Piperazine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for chiral purity and assay, to ensure it meets stringent specifications for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.